Articles tagged with: Stem Cell Transplant

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[ by | Dec 2, 2013 5:12 pm | 2 Comments ]
ASH 2013 Preview: Revlimid Maintenance Therapy For Multiple Myeloma

Results of several studies investigating Revlimid main­te­nance ther­a­py for mul­ti­ple myeloma will be presented at this year’s American Society of Hema­tol­ogy (ASH) annual meeting, which starts later this week.

Today’s article previews the results of the key Revlimid main­te­nance studies that will be presented at the meeting, drawing on findings pub­lished in the meeting abstracts.  Some of the study results, it should be noted, will be updated during the presentations at ASH this week and early next week.

The results to be presented at ASH are unlikely to settle the …

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[ by | Nov 23, 2013 9:04 am | 3 Comments ]
ASH 2013 Preview: Novel Immunotherapies Under Development For The Treatment Of Multiple Myeloma

As The Beacon continues its ‘ASH Preview’ series about myeloma re­search that will be presented at the American Society of Hematology (ASH) meeting in early December, this article focuses on novel im­muno­therapy approaches that are being studied in clinical trials.

Abstracts for the ASH presentations are now available, although many contain pre­lim­i­nary information that will be updated at the meet­ing.

The Beacon’s ASH preview articles are intended to highlight the meet­ing’s most interesting myeloma-related studies.

The first several of the preview articles, which were published over …

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[ by and | Oct 29, 2013 5:40 pm | One Comment ]
Stem Cell Transplantation Effective In Myeloma Patients With Advanced Kidney Disease, But Has Limited Impact On Kidney Function

Findings from a recent retrospective study conducted at the Mayo Clinic indicate that autologous stem cell trans­plan­ta­tion is an effective treat­ment option for multiple myeloma patients with advanced kid­ney disease.

The majority of patients (87 percent) responded to the treatment, with 40 percent achieving a complete response.  According to the researchers, this complete response rate is similar to those seen in other studies of stem cell trans­plan­ta­tion for myeloma patients with kid­ney disease.

However, the researchers found little evidence that trans­plan­ta­tion sig­nif­i­cant­ly improves kid­ney function in patients with advanced kid­ney …

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[ by and | Aug 22, 2013 5:28 pm | One Comment ]
Protein Biomarkers May Predict Onset Of Acute GVHD After Donor Stem Cell Transplantation

Results from a retrospective study demonstrate that a set of protein bio­markers found in urine can be used to predict the development of acute graft-versus-host disease in patients who undergo donor stem cell trans­plan­ta­tion.

During the study, levels of specific urine proteins were used to generate a "classi­fication factor," named aGvHD_MS17, designed to predict a pa­tient's probability of developing acute graft-versus-host disease (GVHD).

The study's findings may allow for early detection and preemptive treat­ment of acute GVHD, a potentially fatal complication that can occur after trans­plan­ta­tion using donor stem cells. …

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[ by and | Aug 21, 2013 4:19 pm | Comments Off ]
Transplantation With Stem Cells Collected After An Initial Transplant May Increase A Myeloma Patient's Risk Of Developing MDS

Results from a recent study indicate that collecting more stem cells prior to a myeloma patient’s first transplant may be beneficial for future trans­plants.

Specifically, relapsed patients who received a second transplant with cells that had been collected prior to their first transplant, rather than those collected following the first transplant, had a lower risk of later developing myelodysplastic syndromes (MDS).

MDS is a group of blood disorders marked by ineffective production of blood cells.  MDS often progresses to acute myeloid leukemia, an ag­gres­sive blood cancer in which the body …

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