Articles tagged with: Neupogen
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Results of a recent Italian study show that Neupogen and Neulasta are comparable in efficacy and safety for the prevention and treatment of low white blood cell counts in multiple myeloma patients receiving outpatient stem cell transplants.
However, patients who were treated with Neulasta only received one injection after the transplant, which according to the study authors may be more convenient for the patients.
“In our experience, the possibility of a single [injection] is more comfortable for patients, mainly in an outpatient regimen,” said Dr. Felicetto Ferrara of the Cardarelli…
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Results of a recent Polish study show that the drug Mozobil may help multiple myeloma patients who previously had a stem cell transplant collect enough stem cells for a second transplant.
However, the results also showed that previously transplanted patients collected fewer stem cells than patients who had not received a stem cell transplant before.
According to the study authors, these results showed for the first time that Mozobil (plerixafor) is highly effective for previously transplanted myeloma patients.
Autologous stem cell transplantation, a common treatment option for younger, newly…
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According to a recent study, omitting growth factor administration following stem cell transplantation results in fewer side effects and less and shorter hospitalization for multiple myeloma patients compared to those who do receive growth factors. In addition, the study authors found that there was little difference between the two groups in the repopulation of white blood cells following transplantation.
According to Dr. Morie Gertz, myeloma expert at the Mayo Clinic in Rochester, Minnesota and lead author of the study, the difference in the repopulation of white blood cells was not…
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A new study in the journal Blood shows that adding Mozobil (plerixafor) to Neupogen (filgrastim) prior to stem cell harvesting significantly increases harvest efficiency.
Mozobil is a new drug designed to mobilize stem cells from the bone marrow into the bloodstream, where they can be collected. Neupogen, which is commonly given prior to stem cell harvesting, stimulates the body to make white blood cells.
When given together, Mozobil and Neupogen have been shown to increase harvest efficiency in myeloma patients prior to autologous peripheral stem cell transplantation. The U.S. Food and…
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Researchers from the Mayo Clinic today reported positive results of a Phase 2 clinical trial combining Actimid (pomalidomide) with low-dose dexamethasone (pom-dex) in relapsed or refractory multiple myeloma patients. The results were presented earlier today at the 50th annual meeting of the American Society of Hematology (ASH).
Actimid, also known as pomalidomide or CC-4047, is a molecular relative of the commonly used myeloma treatment thalidomide (Thalomid). Like thalidomide, Actimid is an immunomodulatory agent, meaning that it has the ability to alter or regulate the body’s immune response.…
