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[ by Funmi Adewale | Feb 4, 2010 11:22 am | No Comment ]
Addition Of Defibrotide To Melphalan-Prednisone-Thalidomide Combination Produces Fewer Side Effects In Multiple Myeloma Patients

A recent study suggests that the addition of defibrotide to the combination regimen of melphalan (Alkeran), prednisone, and thalidomide (Thalomid) may result in fewer side effects in multiple myeloma patients. The Phase 1 clinical trial results were recently published in the journal Haematologica.

With the development of multiple myeloma therapies, the traditional melphalan-prednisone (MP) treatment regimen has been combined with substances such as Velcade (bortezomib) and thalidomide for more effective results. In particular, clinical trials have shown that these new combination treatments produce greater responses…

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