- Name: mayungfer
- Who do you know with myeloma?: Husband
- When were you/they diagnosed?: Dec. 2008
- Age at diagnosis: 59
- Name: Mary Degenkolb
- Who do you know with myeloma?: self
- When were you/they diagnosed?: 2011
- Age at diagnosis: 54
Also any information about Chromosome13 deletion or translocation of other chromosomes in relationship to Rev maint would be appreciated.
Hope and Health to you all.
The IFM study Attal et al. also included a post transplant consolidation with Revlimid/dexamethasone prior to single agent Revlimid -- again, at 10mg daily.
Generally, i initiate maintenance therapy at least 3 months post-transplant and after count recovery at 10mg daily. Though I do have some patients receiving Rev 1-21 of a 28 day cycle. I like to focus on the fact that in the setting of maintenance therapy is personal. Tolerance is a key point. So, if you tolerate 5mg daily, then that is the dose for you.
Generally, we continue Rev for 2 years, but I feel that is a moving target and partly the result/reaction to the increased risk of second primary cancers identified in both post HDM-ASCT trials of maintenance Rev and maintenance post-MPR (melphalan prednisone Revlimid) for transplant ineligible patients.
H. Lee Moffitt Cancer Center & Research Institute
Any advice provided in these postings is based on a very limited amount of information. There is no substitute for the care of your oncologist/hematologist. Therefore, all suggestions should be discussed with your treating physician. None of the comments presented here are meant to replace the evaluation of a patient by a knowledgeable physician.
Dr. Ken Shain
- Name: Ken Shain, M.D., Ph.D.
Beacon Medical Advisor