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Hiccups and Cytoxan
Hello, my Dad recently relapsed and is currently being treated with a Velcade, Cytoxan, Dex combo. He has had hiccups for the last 5 days and is exhausted. His nurse prac./dr. have said this is common. I am wondering if anyone has any tips for relief from the hiccups? He is so exhausted he is actually considering stopping the regimen, but I believe its the depression/sleep depravation talking. Thanks so much!
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Michelle222
Re: Hiccups and Cytoxan
Hi Michelle,
Sorry to hear about your father's bad case of hiccups.
There are various home remedies out there. I personally have had luck with holding my breath for as long as possible. I also know several people who swear by eating ice cream as a solution.
In terms of prescription drugs, the ones I have heard recommended are as follows:
Prochlorperazine (Compazine, Stemetil) - Originally developed as an anti-psychotic; has anti-nausea and anti-seizure effects
Chlorpromazine (Thorazine, Largactil) - Another anti-psychotic that also has anticholinergic effects, meaning that it can counteract nausea but also cause constipation and fatigue
Baclofen (Kemstro, Lioresel) - Muscle relaxant used to treat excessive muscle movement such as the kind associated with cerebral palsy and multiple sclerosis.
All of them seem to work relatively well, but I also don't think they are medications your father will want to be on for an extended period of time.
Best of luck,
Jim
Sorry to hear about your father's bad case of hiccups.
There are various home remedies out there. I personally have had luck with holding my breath for as long as possible. I also know several people who swear by eating ice cream as a solution.
In terms of prescription drugs, the ones I have heard recommended are as follows:
Prochlorperazine (Compazine, Stemetil) - Originally developed as an anti-psychotic; has anti-nausea and anti-seizure effects
Chlorpromazine (Thorazine, Largactil) - Another anti-psychotic that also has anticholinergic effects, meaning that it can counteract nausea but also cause constipation and fatigue
Baclofen (Kemstro, Lioresel) - Muscle relaxant used to treat excessive muscle movement such as the kind associated with cerebral palsy and multiple sclerosis.
All of them seem to work relatively well, but I also don't think they are medications your father will want to be on for an extended period of time.
Best of luck,
Jim
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JimNY
Re: Hiccups and Cytoxan
With myself, it is the dexamethasone that causes the hiccups regardless of what it is combined with; 20 mg is better than 40 mg
In my case I feel that it is caused by delayed gastric emptying as the hiccups onset sometime after eating
Over the years what I have found minimizes or prevents them is to take motilium (domperidome ) 10mg 1/2 hour before meals and at bedtime for 1 -2 days after taking the dexamthasone as it's role is to speed gastric emptying; again 20mg of dexamethasone causes less problems than 40 mg
If hiccups do develop with this, then rebreathing in and out of a paper bag stops them
Being present for 5 days however is a different story and chlorpromazine is a standard used for years; hopefully once resolved you can identify the trigger and find something for prevention.
In my case I feel that it is caused by delayed gastric emptying as the hiccups onset sometime after eating
Over the years what I have found minimizes or prevents them is to take motilium (domperidome ) 10mg 1/2 hour before meals and at bedtime for 1 -2 days after taking the dexamthasone as it's role is to speed gastric emptying; again 20mg of dexamethasone causes less problems than 40 mg
If hiccups do develop with this, then rebreathing in and out of a paper bag stops them
Being present for 5 days however is a different story and chlorpromazine is a standard used for years; hopefully once resolved you can identify the trigger and find something for prevention.
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bond007
Re: Hiccups and Cytoxan
Michelle
It is beyond STOoPId. To even CONSIDER taking anti psychotic meds 4 hiccups. Don't listen 2 such ignorance.
It is beyond STOoPId. To even CONSIDER taking anti psychotic meds 4 hiccups. Don't listen 2 such ignorance.
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harpy
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sunshine
Re: Hiccups and Cytoxan
I got a bad case while I had 2 places in my spine that needed kyphoplasty. Every hiccup caused a spasm 5 seconds apart and I couldn't catch my breath. The worst case hit when out to eat and the friend with me was determined to go to the ER. I didn't, they quieted some, my doc called back with Rx for Thorazine and I take them with me everywhere. Have only used it one other time but it was a life saver! What doc lets you go 5 days with this? Unbelievable!
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Rus
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