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Treatments Under Development

Here you will find a list of current treatments under development:

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Brand Name:
Generic Name: defibrotide
Code Name:
Company: Gentium SpA
FDA Clinical Phase: 1/2

Description:
Defibrotide is an anticoagulant (a drug that prevents blood clotting) that may make myeloma cells more susceptible to chemotherapy. It is not an anti-tumor drug and…

Brand Name:
Generic Name:
Code Name: BI-505
Company: BioInvent
FDA Clinical Phase: 1

Description:
BI-505 is a fully human antibody that causes cell death. It binds to the protein ICAM-1 (CD54), which is more common in tumors than in normal tissue.…

Brand Name:
Generic Name: dacetuzumab
Code Name: SGN-40
Company: Seattle Genetics Inc.
FDA Clinical Phase: 1

Description

Dacetuzumab is a monoclonal antibody that specifically binds to and works against a molecule called a CD40 receptor, which appears in abnormally high amounts in…

Brand Name:
Generic Name:
Code Name: BT-062
Company: Biotest
FDA Clinical Phase: 1/2

Description:
BT-062 (news articles) is a toxic drug bound to an antibody that helps deliver the treatment to myeloma and other cancer cells. When the compound…

Brand Name:
Generic Name: milatuzumab
Code Name:
Company: Immunomedics, Inc.
FDA Clinical Phase: 1/2

Description:
Milatuzumab is a humanized monoclonal antibody that targets tumors expressing the CD74 antigen. As the first anti-CD74 antibody studied in human clinical trials,…

Brand Name:
Generic Name:
Code Name: AT9283
Company: Astex
FDA Clinical Phase: 2

Description:
AT9283 is a kinase inhibitor that prevents cell division, thereby stopping the growth of cancer cells. Several Phase 1 clinical trials have shown that AT9283 is safe…

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