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Treatments Under Development

Here you will find a list of current treatments under development:

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Brand Name: Afinitor
Generic Name: everolimus
Code Name: RAD001
Company: Novartis
FDA Clinical Phase: 1/2

Description:
Afinitor was approved by the FDA in March 2009 for the treatment of advanced renal cell carcinoma, but it is currently also being studied in multiple myeloma.…

Brand Name:Aplidin
Generic Name:plitidepsin
Code Name:
Company:PharmaMar, SA
FDA Clinical Phase:3
Description: Aplidin is derived from a compound found in tunicates which shows promise in shrinking tumors. The specific marine organism is Aplidium albicans.
Brand Name:Atiprimod
Generic Name:azaspirane
Code Name:SK&F106615
Company:Callisto Pharmaceuticals
FDA Clinical Phase:1/2
Description: A substance being studied in the treatment of certain multiple myelomas and other advanced cancers. Atiprimod may block the growth of tumors and the growth of new blood vessels that tumors need to grow. Atiprimod is a type of signal transduction inhibitor.
Brand Name:Avastin
Generic Name:bevacizumab
Code Name:rhuMAb-VEGF
Company:Genentech Inc.
FDA Clinical Phase:1/2
Description: Avastin is a monoclonal antibody used in the treatment of colorectal cancer that has spread. It is also being studied in the treatment of other types of cancer. Avastin binds to vascular endothelial growth factor (VEGF) and may stop the growth of new blood vessels needed for tumors to grow. It is a type of antiangiogenesis agent.
Brand Name:Bexxar
Generic Name:iodine I 131 tositumomab
Code Name:
Company:GlaxoSmithKline
FDA Clinical Phase:2
Description: Bexxar is a monoclonal antibody to which radioactive iodine 131 is attached, which targets a protein called CD20 found on the surface of a variety of B-cells, including lymphoma cells, and some myeloma cells. The radioactive iodine attached to the antibody delivers radiation directly to these cells which works to harm or kill the cancer cells. Approximately 20-25% of patients with multiple myeloma have this protein on the surface of their tumor cells.
Brand Name:Doxil
Generic Name:doxorubicin HCl liposome injection
Code Name:
Company:Ortho Biotech
FDA Clinical Phase:1, 2, & 3
Description: A form of the anticancer drug doxorubicin that is contained in very tiny, fat-like particles. It may have fewer side effects and work better than doxorubicin. Doxil is used to treat ovarian cancer, AIDS-related Kaposi sarcoma, and multiple myeloma in patients whose disease has not gotten better after treatment with other anticancer drugs. It may be used together with other anticancer drugs. It is also being studied in the treatment of other types of cancer. Doxil is a type of anthracycline antitumor antibiotic.
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