An ongoing Phase 2 trial of carfilzomib has demonstrated that carfilzomib may be effective in treating relapsed/refractory multiple myeloma patients, including patients who are resistant to or relapsed after Velcade (bortezomib) treatment. The results were presented by Dr. Ravi Vij of Washington University in St. Louis at the annual American Society of Clinical Oncology (ASCO) meeting in Chicago on June 5.
“Single agent carfilzomib has demonstrated significant activity in relapsed/refractory myeloma,” said Dr. Vij during his presentation.
Carfilzomib,…
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The combination treatment of reduced-dose Velcade (bortezomib), thalidomide (Thalomid), and dexamethasone (Decadron), abbreviated vTD, appears to be a safe and effective induction treatment for newly diagnosed multiple myeloma patients prior to stem cell transplantation.
The combination treatment yielded higher complete and partial remission rates, and fewer and less severe side effects, than treatment with standard dose Velcade plus dexamethasone (VD).
The vTD vs. VD findings were presented by Dr. Philippe Moreau of the University Hospital in Nantes,…
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