Melissa Cobleigh's Archive

melissa.cobleigh@light-kr.com

 Melissa Cobleigh is a fifth year graduate student at Yale University pursuing her Ph.D. in molecular medicine. Her research focuses on the development of a novel vaccine for the prevention and treatment of hepatitis B virus. Melissa is originally from Maine and before coming to Yale attended Smith College where she received her bachelor’s degree in biochemistry. Melissa joined the Myeloma Beacon in June 2010. In her spare time, Melissa enjoys reading, long walks, and anything related to the ocean.

Melissa Cobleigh has written 15 article(s).

Oral Busulfan Treatment May Be More Effective But Not As Safe As Melphalan Prior To Stem Cell Transplant In Multiple Myeloma Patients
[ by Melissa Cobleigh | Aug 31, 2010 4:40 pm | No Comments ]
Oral Busulfan Treatment May Be More Effective But Not As Safe As Melphalan Prior To Stem Cell Transplant In Multiple Myeloma Patients

In a recent study, Spanish researchers found that oral busulfan increased progression-free survival following stem cell transplant in newly diagnosed multiple myeloma patients compared to melphalan. However, there was no difference in overall survival between the two treatments.  Furthermore, oral busulfan treatment was associated with an increased risk of death due to the drug’s side effects.

The current standard of care for multiple myeloma patients under the age of 65 is treatment with high dose chemotherapy followed by stem cell…

Read the full story »
Etoposide Is Highly Effective For Stem Cell Mobilization In Multiple Myeloma Patients
[ by Melissa Cobleigh | Aug 23, 2010 5:17 pm | No Comments ]
Etoposide Is Highly Effective For Stem Cell Mobilization In Multiple Myeloma Patients

Results of a recent study suggest that etoposide used in combination with G-CSF is a safe and effective mobilization strategy prior to stem cell transplantation in multiple myeloma patients. The combination treatment resulted in a high stem cell harvest after one day of collection in most patients.

Stem cell mobilization is the process of increasing the number hematopoietic (blood forming) stem cells in the circulating blood to ensure that enough are available to be collected for the transplant. Hematopoietic stem…

Read the full story »
MGUS And Smoldering Multiple Myeloma: Experts Identify Risk Factors For Disease Progression And Establish Monitoring Guidelines – Part 2: Smoldering Myeloma
[ by Melissa Cobleigh | Aug 18, 2010 2:19 pm | No Comments ]
MGUS And Smoldering Multiple Myeloma: Experts Identify Risk Factors For Disease Progression And Establish Monitoring Guidelines – Part 2: Smoldering Myeloma

The International Myeloma Working Group, a group of top myeloma doctors, recently published a report identifying risk factors for disease progression in patients with the multiple myeloma precursor diseases, monoclonal gammopathy of undetermined significance and smoldering myeloma. In addition, the myeloma experts established guidelines for the monitoring and management of these two conditions.  This article, Part 2 in a series, covers the results for smoldering myeloma. Part 1 covers the results for myeloma monoclonal gammopathy of undetermined significance.

The…

Read the full story »
MGUS And Smoldering Multiple Myeloma: Experts Identify Risk Factors For Disease Progression And Establish Monitoring Guidelines – Part 1: MGUS
[ by Melissa Cobleigh | Aug 16, 2010 5:59 pm | No Comments ]
MGUS And Smoldering Multiple Myeloma: Experts Identify Risk Factors For Disease Progression And Establish Monitoring Guidelines – Part 1: MGUS

The International Myeloma Working Group, a group of top myeloma doctors, recently published a report identifying risk factors for disease progression in patients with the multiple myeloma precursor diseases, monoclonal gammopathy of undetermined significance and smoldering myeloma. In addition, the myeloma experts established guidelines for the monitoring and management of these two conditions.  This article, Part 1 in a series, covers the results for monoclonal gammopathy of undetermined significance. Part 2 will cover the results for smoldering myeloma.

The…

Read the full story »
Page 1 of 41234»